14. Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, Zon LI: Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America 2007; 104: 9410e9415

15. Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF: A zebrafish transgenic model of Ewing’s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Dis Mod Mech 2012; 5: 95e106

16. Lohberger B, Stuendl N, Leithner A et al.: Establishment of a novel cellular model for myxofibrosarcoma heterogeneity. Sci Rep 2017; 7: 44700

17. Ottaviano L, Schaefer K-L, Gajewski M et al.: Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort. Genes Chromosomes Cancer 2010; 49: 40–51

18. Pauli C, Hopkins BD, Prandi D et al.: Personalized in vitro and in vivo cancer models to guide precision medicine. Cancer Discov 2017; 7: 462–77

19. Salawu A, Fernando M, Hughes D et al.: Establishment and molecular characterisation of seven novel soft-tissue sarcoma cell lines. Br J Cancer 2016; 115: 1058–68

20. Salerno M, Avnet S, Bonuccelli G et al.: Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas. Int J Oncol 2013; 43: 95–102

21. Santoriello C, Deflorian G, Pezzimenti F et al.: Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells. Dis Mod Mech 2009; 2: 56e67

22. Schmeichel KL, Bissell MJ: Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci 2003; 116: 2377–88

23. Stebbing J, Paz K, Schwartz GK et al.: Patient-derived xenografts for individualized care in advanced sarcoma. Cancer 2014; 120: 2006–15

24. Stiller CA, Trama A, Serraino D et al.: Descriptive epidemiology of sarcomas in Europe: report from the RARECARE project. Eur J Cancer 2013; 49: 684–95

25. Storer NY, White RM, Uong A et al.: Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development 2013; 140: 3040e3050

26. van der Kuip H, Mürdter TE, Sonnenberg M et al.: Short term culture of breast cancer tissues to study the activity of the anticancer drug taxol in an intact tumor environment. BMC Cancer 2006; 6: 86

27. Voissiere A, Jouberton E, Maubert E et al.: Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing. PLoS One 2017; 12: e0181340

28. Wu Z, Min L, Chen D et al.: Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma. PLoS One 2011; 6: e14648

Fussnoten

2 Biomedizinische Forschung, Core Facility Alternative Biomodels und Preclinical Imaging, Medizinische Universität Graz, Österreich

3 Institut für Pathologie, Medizinische Universität Graz, Österreich