8. Brun P, Dickinson SC, Zavan B, Cortivo R, Hollander AP, Abatangelo G: Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation. Arthritis Res Ther 2008; 10: R132

9. Crawford DC, DeBerardino TM, Williams RJ 3rd: NeoCart, an autologous cartilage tissue implant, compared with microfracture for treatment of distal femoral cartilage lesions: an FDA phase-II prospective, randomized clinical trial after two years. J Bone Joint Surg Am 2012; 94: 979–89

10. Deng Z, Jin J, Zhao J, Xu H: Cartilage defect treatments: with or without cells? Mesenchymal stem cells or chondrocytes? Traditional or matrix-assisted? A systematic review and meta-analyses. Stem Cells Int 2016; 2016: 9201492

11. Desando G, Bartolotti I, Vannini F et al.: Repair potential of matrix-induced bone marrow aspirate concentrate and matrix-induced autologous chondrocyte implantation for talar osteochondral repair: patterns of some catabolic, inflammatory, and pain mediators. Cartilage 2017; 8: 50–60

12. de Windt TS, Vonk LA, Brittberg M, Saris DB: Treatment and prevention of (early) osteoarthritis using articular cartilage repair-fact or fiction? A systematic review. Cartilage 2013; 4 (3 Suppl): 5S–12S

13. DiBartola AC, Everhart JS, Magnussen RA et al.: Correlation between histological outcome and surgical cartilage repair technique in the knee: A meta-analysis. Knee 2016; 23: 344–9

14. EU-Kommissionsentwurf „Advanced Therapies“. Gemeinsame Stellungnahme der DGU und DGOOC. Orthopädie Mitteilungen 2006; 4: 323–6

15. Feldman MD: Editorial Commentary: All that glitters is not gold. Arthroscopy 2016; 32: 348–9

16. Fickert S, Aurich M, Albrecht D et al.: Biologische Rekonstruktion lokalisiert vollschichtiger Knorpelschäden des Hüftgelenks: Empfehlungen der Arbeitsgemeinschaft „Klinische Geweberegeneration“ der DGOU und des Hüftkomitees der AGA. Z Orthop Unfall 2017; 155: 670–82

17. Frank RM, McCormick F, Rosas S et al.: Reoperation rates after cartilage restoration procedures in the knee: analysis of a large US commercial database. Am J Orthop (Belle Mead NJ) 2018; 47

18. Harris JD, Siston RA, Brophy RH, Lattermann C, Carey JL, Flanigan DC: Failures, re-operations, and complications after autologous chondrocyte implantation – a systematic review. Osteoarthritis Cartilage 2011; 19: 779–91

19. Haubold H, Theysohn J, Geis C et al.: 3T-MRT zur Verlaufsbeurteilung nach hüftgelenkserhaltender Knorpeltherapie – Vergleich zwischen autologer Chondrozytentransplantation und Mikrofrakturierung. Fortschr Röntgenstr 2017; 189: S1–S124

20. Heir S, Nerhus TK, Røtterud JH et al.: Focal cartilage defects in the knee impair quality of life as much as severe osteoarthritis. Am J Sports Med 2010; 38: 231–7

21. Henderson I, Lavigne P, Valenzuela H, Oakes B: Autologous chondrocyte implantation: superior biologic properties of hyaline cartilage repairs. Clin Orthop Relat Res 2007; 455: 253–61

22. Minas T, Ogura T, Headrick J, Bryant T: Autologous chondrocyte implantation “sandwich“ technique compared with autologous bone grafting for deep osteochondral lesions in the knee. Am J Sports Med 2018; 46: 322–32

23. Mistry H, Connock M, Pink J et al.: Autologous chondrocyte implantation in the knee: systematic review and economic evaluation. Health Technol Assess 2017; 21: 1–294

24. Niemeyer P, Albrecht D, Andereya S et al.: Autologous chondrocyte implantation (ACI) for cartilage defects of the knee: a guideline by the working group “clinical tissue regeneration“ of the german society of orthopaedics and trauma (DGOU). Knee 2016; 23: 426–35

25. Riboh JC, Cvetanovich GL, Cole BJ, Yanke AB: Comparative efficacy of cartilage repair procedures in the knee: a network meta-analysis. Knee Surg Sports Traumatol Arthrosc 2017; 25: 3786–99

26. Sanders TL, Pareek A, Obey MR et al.: High rate of osteoarthritis after osteochondritis dissecans fragment excision compared with surgical restoration at a mean 16-year follow-up. Am J Sports Med 2017; 45: 1799–805

27. Saris D, Price A, Widuchowski W et al.: SUMMIT study group. Matrix-applied characterized autologous cultured chondrocytes versus microfracture: two-year follow-up of a prospective randomized trial. Am J Sports Med 2014; 42: 1384–94

28. Welch T, Mandelbaum B, Tom M: Autologous chondrocyte implantation: past, present, and future. Sports Med Arthrosc 2016; 24: 85–91

29. Wylie JD, Hartley MK, Kapron AL, Aoki SK, Maak TG: What is the effect of matrices on cartilage repair? A systematic review. Clin Orthop Relat Res 2015; 473: 1673–82

30. Zhang C, Cai YZ, Lin XJ: Autologous chondrocyte implantation: Is it likely to become a saviour of large-sized and full-thickness cartilage defect in young adult knee? Knee Surg Sports Traumatol Arthrosc 2016; 24: 1643–50